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. 2018 Jul 20;16:205. doi: 10.1186/s12967-018-1577-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The performance of biomarkers. a The horizontal axis is the number of selected features. The vertical axis is the corresponding accuracy. b The red curve is the initial model accuracy without optimization. The green curve is the accuracy of the model after feature selection and parameter optimization. The blue curve is the average accuracy calculated using a fivefold cross-validation method. c The survival analysis. The horizontal axis is the survival time (month). The vertical axis is the percentage of patients in different groups