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. 2018 Jul 20;15:50. doi: 10.1186/s12977-018-0431-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Infectivity and neutralization assays of 4-2.J41 mutant Env pseudotyped viruses. a Infectivity of 4-2.J41 Env wild type and deletion mutant pseudoviruses using TZM-bl reporter based cell assay. b IC₅₀ values of 4-2.J41 wild type and deletion mutant Env pseudotyped viruses with the cleavage non-specific bNAb VRC01, glycan-dependent and conformational bNAb, PG9, trimer-selective and cleavage-specific bNAb, PGT151, MPER-directed bNAbs, 10E8 and 4E10. c IC₅₀ values of 4-2.J41 wild type and deletion mutant Env pseudotyped viruses with bNAbs, PGT121 and PGT145 (left panel) and non-NAbs F105 and 17b at 37 and 4 °C (right panel)