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. 2018 May 3;8:35–44. doi: 10.2147/DNND.S161450

Figure 1.

Figure 1

Immunopathogenesis of multiple sclerosis and associated immune targets.

Abbreviations: APC, antigen presenting cell; HLA, human leukocyte antigen; IFN, interferon; IL, interleukin; MHC, major histocompatibility complex; MMP, matrix metalloproteinase; NO, nitric oxide; ROS, reactive oxygen species; TCR, T-cell receptor; Th, T helper cell; Treg, regulatory T cell.