The expression of P-P38 in the synovial membranes. Immunohistochemical staining for P-p38 in the synovial membranes of (A) the control group, (B) the occlusal interference group, and (C) the SB203580 group. (D) The mean optical density of each group. As the results show, in comparison with the control group, the expression of P-p38 was significantly increased in the occlusal interference group. However, this effect could be inhibited significantly after treatment with the SB203580. Data shows all the values from independent samples of n=6, * P<0.05 vs. control group, #
P<0.05 vs. occlusal interference group.