Figure 2.

Analyses of lymphovascular invasion in primary breast tumors indicated increased intratumoral lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) microvessel density in tumors from socially isolated women. A) Representative images of LYVE-1-stained sections from patients reporting high vs low social isolation. B) Box plots of predicted scores for LYVE-1 microvessel density in the high– and low–social isolation groups. Each box indicates the interquartile range, and the middle line indicates the median for that group. LYVE-1 = lymphatic vessel endothelial hyaluronan receptor 1.