Table 3.

The effects of diazinon, saffron treatment (for 4 weeks) on biochemical indices.

Parameter	Total bilirubin mg/dl	direct bilirubin mg/dl	ALb g/dl	Protein g/dl	TG mg/dl	Cholestrol mg/dl	uric acid mg/dl	creatinine mg/dl	Urea mg/dl
Control	0.6 ± 0.06	0.4 ± 0.06	4.3 ± 0.19	7.5 ± 0.34	71.6 ± 5.1	72.7 ± 6.9	2.5 ± 0.26	1.15 ± 0.09	51.0 ± 3.0
Diazinon(DZN) 20 mg/kg	0.8 ± 0.09	0.3 ± 0.04	3.8 ± 0.28	+ 5.8 ± 0.38	74.0 ± 7.4	75.5 ± 7.2	+ 5.3 ± 0.36	1.23 ± 0.11	54.3 ± 3.4
Vitamin E 200 IU/kg	0.5 ± 0.03	0.3 ± 0.05	4.1 ± 0.28	6.3 ± 0.33	79.8 ± 4.3	74.0 ± 7.6	* 3.1 ± 0.16	1.16 ± 0.14	53.3 ± 3.8
DZN + Vitamin E	0.6 ± 0.08	0.3 ± 0.05	3.5 ± 0.25	6.1 ± 0.45	87.0 ± 8.4	72.3 ± 5.3	5.0 ± 0.70	1.28 ± 0.12	48.6 ± 3.3
Saffron 50 mg//kg	0.5 ± 0.05	0.3 ± 0.04	4.3 ± 0.14	**7.8 ± 0.36	69.2 ± 8.2	72.8 ± 5.7	3.8 ± 0.19	1.20 ± 0.13	57.2 ± 5.0
Saffron 100	0.5 ± 0.06	0.2 ± 0.04	4.2 ± 0.19	*7.6 ± 0.25	70.8 ± 5.1	73.6 ± 4.9	+++ 6.2 ±0.28	1.20 ± 0.13	54.3 ± 4.5
Saffron 200 mg/kg	0.5 ± 0.07	0.2 ± 0.06	4.1 ± 0.18	***7.9 ± 0.34	74.0 ± 5.5	72.5 ± 5.5	+++ 6.0 ±0.32	1.4 ± 0.10	54.7 ± 4.1
DZN + Saffron 50 mg/kg	0.6 ± 0.04	0.3 ± 0.05	4.2 ± 0.30	+++ 5.2 ±0.27	68.7 ± 2.7	74.3 ± 4.9	*** 2.7± 0.25	1.20 ± 0.12	54.1 ± 4.6
DZN+ Saffron 100 mg/kg	0.5 ± 0.07	0.3 ± 0.03	4.1 ± 0.19	7.0 ± 0.35	73.5 ± 5.5	76.0 ± 4.0	+++ 5.7± 0.30	1.20 ± 0.09	55.0±5.0
DZN+ Saffron 200 mg/kg	0.6 ± 0.06	0.2 ± 0.05	3.9 ±0.14	6.9 ± 0.31	78.8 ± 6.7	74.8 ± 4.6	+++ 5.8 ±0.36	1.30 ± 0.12	53.0 ± 4.4

Data showed as mean ± SEM, + Comparison with control, *Comparison with diazinon treated group.+ or *P< 0.05, ++ or **P< 0.01, +++ or *** P<0.001, Tukey Kramer test, n=6.