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. 2015 Jul 22;6(11):6312–6319. doi: 10.1039/c5sc01914a

Table 3. Scope of aromatic and alkyl substituents.

Inline graphic
Entry Starting material Product Yield a
1 graphic file with name c5sc01914a-u6.jpg graphic file with name c5sc01914a-u7.jpg 90% (1 h)
2 graphic file with name c5sc01914a-u8.jpg graphic file with name c5sc01914a-u9.jpg 84% (1 h)
3 graphic file with name c5sc01914a-u10.jpg graphic file with name c5sc01914a-u11.jpg 88% (1 h)
4 graphic file with name c5sc01914a-u12.jpg graphic file with name c5sc01914a-u13.jpg 90% (1 h)
5 graphic file with name c5sc01914a-u14.jpg graphic file with name c5sc01914a-u15.jpg 93% (1 h)
6 graphic file with name c5sc01914a-u16.jpg graphic file with name c5sc01914a-u17.jpg 31% b (1 h)
7 graphic file with name c5sc01914a-u18.jpg graphic file with name c5sc01914a-u19.jpg 80% (1 h)
8 graphic file with name c5sc01914a-u20.jpg graphic file with name c5sc01914a-u21.jpg 80% (18 h)
9 graphic file with name c5sc01914a-u22.jpg graphic file with name c5sc01914a-u23.jpg 46% c , d 3 : 2 rr e (26 h)
10 graphic file with name c5sc01914a-u24.jpg graphic file with name c5sc01914a-u25.jpg 65% c 1 : 1 rr e (22 h)
11 graphic file with name c5sc01914a-u26.jpg graphic file with name c5sc01914a-u27.jpg 88% (1 h)
12 graphic file with name c5sc01914a-u28.jpg graphic file with name c5sc01914a-u29.jpg 80% c 3 : 1 rr e (1 h)
13 graphic file with name c5sc01914a-u30.jpg graphic file with name c5sc01914a-u31.jpg 78% c 4 : 1 rr e (1 h)

aIsolated yield of products 26 after flash chromatography.

bThe low yield was attributed to poor solubility of the product in most organic solvents.

cCombined yield for both regioisomers.

dThe major regioisomer was not assigned, as these compounds were not separable by chromatography.

eThe ratio of regioisomers was determined by 1H NMR of the crude reaction mixture.