Table 1.

Inclusion and Exclusion Criteria.

Inclusion Criteria
1	Fulfilling the diagnostic criteria for AN (restrictive or binge-eating/purging subtype) or Eating disorder not otherwise specified (EDNOS), according to the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, text revision), and weighing 85% or less of his or her TGW.
2	Aged 11 to 17 years, inclusive.
3	Receiving medical and psychological treatment from the Eating Disorder Program at our center.
Exclusion Criteria
4	Currently receiving treatment with any other antipsychotic medication, mood stabilizer, or stimulant.
5	Known diagnosis of diabetes, impaired glucose tolerance, hyperlipidemia, hepatic dysfunction, substance dependence, narrow angle glaucoma, paralytic ileus, pancreatitis, or any other medical illness that would be considered to significantly impact treatment or recovery from the eating disorder.
6	Inability to comply with trial requirements including lack of comprehension of English.
7	Pregnant or breast-feeding.
8	Known allergy or known sensitivity to products in olanzapine.
9	Other unspecified reasons that, in the opinion of the investigator, make the patient unsuitable for enrolment.
10	Liver function tests (AST/ALT) > 2× normal.
11	Electrocardiogram: QTc > 450 msec or arrhythmia other than sinus bradycardia; conduction abnormalities prolonged QTc or other.
12	LDL-C > 4.9 mmol/L; (10) Total cholesterol/HDL ratio > 6.
13	Random glucose > 11 mmol/L (or Fasting glucose ≥ 6.1 mmol/L).
14	Neutrophil count < 0.5 × 109/L.

^aNote that all of these patients would now meet DSM-5 criteria for anorexia nervosa.

ALT = Alanine aminotransferase. AST = Aspartate aminotransferase. HDL = High density lipoprotein cholesterol. LDL-C = Low density lipoprotein cholesterol. QTc = Corrected QT interval. TGW = Treatment goal weight.