Transformation matrix and performances |
where Covariance matrix of the polygenic matrix K and environmental noise are whitened.Number of nonzero eigenvalues is specified as one. |
Shrinkage is selective. Large effects subject to virtually no shrinkage while small effects are shrunken to zero. |
One-dimensional optimization by deriving the likelihood as a function of QTN-to-residual variance ratio. |
Kinship among individuals is replaced by the kinship among groups.Fit the groups as the random effect, and estimates population parameters only once and then fixes them to test genetic markers. |
Kinship among individuals is replaced by the kinship among groups.Chooses the best combination between kinship algorithms and grouping algorithms. |
Dramatically reduces the number of markers used to define individual relationships, and uses them in FaST-LMM. |