Table S1.

In vitro antifungal activity of peptide SP-E and its shortened derivatives SP-E22 and SP-E13 against reference yeast strains

Peptide	Fungal strains	EC50 (mol/L)	95% CI	EC50/EC50 SP-E
SP-E	Cryptococcus neoformans 6995	2.215×10−6	1.634–3.003×10−6
	Candida albicans SC5314	2.581×10−5	1.658–4.018×10−5
SP-E22	C. neoformans 6995	8.304×10−6	6.532–10.559×10−6	3.75
	C. albicans SC5314	3.904×10−5	1.984–7.678×10−5	1.51
SP-E13	C. neoformans 6995	12.251×10−6	9.553–15.715×10−6	5.53
	C. albicans SC5314	6.638×10−5	4.194–10.504×10−5	2.57

Notes: EC₅₀ calculated by nonlinear regression analysis using GraphPad Prism 4.01 software. Fungicidal activity in vitro assessed by colony-forming unit assays, as previously described.²¹