Table 2.

Comparison of VFI mGFR with iohexol mGFR, and eGFR by CKD-EPI and MDRD formulas in all four cohorts

Cohort	Participant ID	Iohexol mGFR, ml/min per 1.73 m2	FAST mGFR, ml/min per 1.73 m2	Creatinine, mg/dl	CKD-EPI eGFR, ml/min per 1.73 m2	MDRD eGFR, ml/min per 1.73 m2	FAST PV, ml
Cohort 1: healthy participants	1009	N/A	111	0.6	133	129	2115
	1010		73	1.1	71	67	3050
	1011		87	1.0	83	77	3187
	1012		112	0.7	120	109	3443
	1013		77	0.7	89	83	2775
	1014		89	0.7	101	88	3057
	1015		113	0.7	135	119	2649
	1016		102	0.6	108	107	2667
Cohort 2: healthy participants; repeat VFI dose	1001	97	96	0.9	119	104	2632
			97		119	104
	1002	82	82	0.7	89	83	2294
			83		89	83
	1003	79	78	0.7	101	114	3226
			74		101	114
	1004	82	84	1.1	87	77	2487
			87		87	77
	1005	114	113	0.5	95	120	2457
			119		95	120
	1006	72	72	0.7	101	89	2462
			71		101	89
	1007	77	77	0.8	80	73	2335
			79		80	73
	1008	99	97	0.6	103	134	2457
			95		103	134
Cohort 3: 30≤eGFR<60 ml/min per 1.73 m2	2001	58	56	1.4	51	50	3609
	2004	36	37	1.1	58	52	2247
	2005	52	51	1.2	59	59	3288
	2006	56	58	1.0	57	55	2224
	2007	55	54	1.4	49	69	4181
	2016	37	37	1.8	34	35	2505
	1017	39	42	1.5	46	46	3347
	1018	49	50	1.9	46	45	3458
Cohort 4: 15≤eGFR<30 ml/min per 1.73 m2	2003	32	33	2.9	26	39	3631
	2009	17	18	3.4	20	22	6234
	2010	29	31	1.7	29	29	3042
	2011	24	28	3.2	20	19	3204
	2012	23	25	2.7	23	23	3057
	2014	24	22	3.3	21	20	3556
	2015	31	32	2.2	28	28	2899
	2017	26	28	2.6	25	24	3409

CKD EPI, CKD Epidemiology Collaboration Equation; MDRD, Modification of Diet in Renal Disease equation; FAST PV, visible fluorescent injectate–based plasma volume measurement; N/A, not applicable.