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. 2018 Jul 20;13(7):e0200893. doi: 10.1371/journal.pone.0200893

Table 1. Patient demographics.

EA (n = 165) Non-EA (n = 834) p
Age, year 65 ± 13 65 ± 14 0.889
Sex, male 112 (67.9%) 500 (60.0%) 0.056
BMI, kg·m-2 23.7 ± 3.9 23.0 ± 3.5 0.080
ASA ≥ 3 60 (36.4%) 327 (39.2%) 0.493
Comorbidites
    Diabetes 33 (20.0%) 170 (20.4%) 0.911
    Coronary artery disease 11 (6.7%) 61 (7.3%) 0.769
    Heart failure 10 (6.1%) 34 (4.1%) 0.256
    Stroke 9 (5.5%) 48 (5.8%) 0.879
    Chronic kidney disease 15 (9.1%) 123 (14.7%) 0.054
Pretreatment CEA, μg·L-1 19.7 (3.5–82.8) 18.4 (4.1–92.0) 0.632
Tumor location 0.270
    Right-sided colon 48 (29.1%) 265 (31.8%)
    Left-sided colon 61 (37.0%) 338 (40.5%)
    Rectum 56 (33.9%) 231 (27.7%)
Anesthesia time, min 300 (255–390) 315 (255–390) 0.567
pRBC transfusion 0.350
    No transfusion 101 (61.2%) 476 (57.1%)
    ≦4 units 46 (27.9%) 259 (31.1%)
    > 4 units 18 (10.9%) 99 (11.9%)
Preoperative C/T ± R/T 15 (9.1%) 140 (16.8%) 0.013
Postoperative C/T (< 90 days) 0.002
    Nil 13 (7.9%) 97 (11.6%)
    Pure C/T 89 (53.9%) 328 (39.3%)
  C/T + TT 63 (38.2%) 409 (49.0%)
Postoperative R/T (< 90 days) 24 (14.5%) 86 (10.3%) 0.112
Follow-up time, months 18.3 (6.8–35.5) 17.4 (7.6–31.0) 0.370

Values were mean ± SD, counts (percent), or median (interquartile range). Continuous variables are analyzed with Wilcoxon rank-sum tests; categorical variables are analyzed with Pearson chi-square tests or Mann-Whitney U tests, as appropriate. BMI: body mass index; ASA physical status: American Society of Anesthesiologists physical status; CEA: carcinoembryonic antigen; pRBC: packed red blood cell; C/T: chemotherapy; TT: target therapy; R/T: radiotherapy.