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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Mol Microbiol. 2017 Jul 23;105(6):860–868. doi: 10.1111/mmi.13741

Figure 6. Functional chaperone balance is not restored by overexpressing Ydj1 or Ssb1.

Figure 6

(A) Ydj1 is an Hsp40 J-protein that enhances Ssa1 ATPase activity. Overexpressing Ydj1 with Sup35 and Ssa1 is more toxic than Sup35 and Ssa1 overexpression alone. The EV strain contains LEU2-, TRP1-, and URA3-marked empty vectors. (B) Ydj1 overexpression alone is not toxic. The co-overexpression of Ssa1 and Ydj1 is not toxic without Sup35 overexpression.