Table 1. Optimization conditions.

Formulations used to design cortisol-selective polymers.

The values are calculated by taking the ratio of slope of each sensor calibration curve for each molecularly imprinted and nonimprinted control polymer (Fig. 3, B and C, and figs. S1 to S5). The starting concentration of cortisol is 0.2 mmol in each condition. Control polymers are not included in the table; they were prepared exactly as corresponding selective polymer but without the template. AIBN, azobisisobutyronitrile.

Membrane	Monomer	Cross-linker	Initiator	Solvent	Ratio*	Conditions	Sensing factor†
A1618	MAA	EDMA	AIBN	Acetonitrile	1:6:18	UV, 4°C, 30 hours	4.2
M1618	MAA	EDMA	AIBN	Methanol	1:6:18	UV, 4°C, 30 hours	5.1
D1618	MAA	EDMA	AIBN	DCM	1:6:18	UV, 4°C, 30 hours	5.4
D1630	MAA	EDMA	AIBN	DCM	1:6:30	UV, 4°C, 30 hours	10.1
D1660	MAA	EDMA	AIBN	DCM	1:6:60	UV, 4°C, 30 hours	2.2
D1630RT	MAA	EDMA	AIBN	DCM	1:6:30	UV, room temperature, 30 hours	6.7

*Molar ratio of template/functional monomer/cross-linker.

†Calculated based on each sensor device’s performance to express imprinting efficiency.