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. 2018 Apr 2;11(3):653–663. doi: 10.1016/j.tranon.2018.03.001

Figure 6.

Figure 6

Evaluation of the candidate signaling pathway nominated by the KEGG analysis. (A) rt-qPCR analyses of the candidate hypomethylated genes; (B) rt-qPCR analyses of Pik3cg (top) and Pik3ca (bottom); ***P < .001, **P < .01, *P < .05. (a, miPSCs; b, miPS-LLCcm cells; c, Ptdc cells; d, LMN cells). (C) Immunoblotting analysis of AKT activation and the expression of Pik3r5.