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. 2018 Jul 20;8:10966. doi: 10.1038/s41598-018-29298-6

Table 1.

Amino acid sequences and properties of CPPs used in this study.

Peptide No. CPP Amino acid sequence Number of amino acids CPP typea Net charge at pH7 Reference
1 BP100 KKLFKKILKYL 11 A 5 20
2 2BP100 KKLFKKILKYLKKLFKKILKYL 22 C 10 17
3 Rev(34–50) TRQARRNRRRRWRERQR 17 C 9 47
4 R9 RRRRRRRRR 9 C 9 48
5 D-R9 rrrrrrrrr (D form) 9 C 9 49
6 R12 RRRRRRRRRRRR 12 C 12 this study
7 KH9 KHKHKHKHKHKHKHKHKH 18 C 9.9 50
8 K9 KKKKKKKKK 9 C 9 this study
9 K18 KKKKKKKKKKKKKKKKKK 18 C 18 this study
10 Pen2W2F RQIKIFFQNRRMKFKK 16 C 7 51
11 DPV3 RKKRRRESRKKRRRES 16 C 10 52
12 6-Oct GRKRKKRT 8 C 6 53
13 R9-TAT GRRRRRRRRRPPQ 13 C 9 47
14 Tat(49–57) RKKRRQRRR 9 C 8 49
15 Retro - Tat(57–49) RRRQRRKKR 9 C 8 49
16 Sc18 GLRKRLRKFRNKIKEK 16 A 8 54
17 KLA10 KALKKLLAKWLAAAKALL 18 A 5 55
18 IX QLALQLALQALQAALQLA 18 H 0 55
19 XI LKTLATALTKLAKTLTTL 18 H 3 55
20 No. 14–12 RAWMRWYSPTTRRYG 15 A 4 56
21 pVEC LLIILRRRIRKQAHAHSK 18 A 6.2 57
22 PenArg RQIRIWFQNRRMRWRR 16 A 7 51
23 M918 MVTVLFRRLRIRRACGPPRVRV 22 A 6.9 58
24 Penetratin RQIKIWFQNRRMKWKK 16 A 7 59
25 PolyP 3 (SAP) VRLPPPVRLPPPVRLPPP 18 H 3 60
26 dhvar5 LLLFLLKKRKKRKY 14 A 7 61
27 HPV33L2-445/467 SYFILRRRRKRFPYFFTDVRVAA 23 A 6 62
28 buforin II (5–21) RAGLQFPVGRVHRLLRK 17 A 5.1 63
29 scrambled pVEC IAARIKLRSRQHIKLRHL 18 A 6.2 64
30 HPV33L2-DD447 SYDDLRRRRKRFPYFFTDVRVAA 23 A 4 62
31 LAH4 KKALLALALHHLAHLALHLALALKKA 26 H 4.4 65
32 ppTG1 GLFKALLKLLKSLWKLLLKA 20 A 5 66
33 Transportan (TP) GWTLNSAGYLLGKINLKALAALAKKIL 27 H 4 67
34 2 × ppTG1 GLFKALLKLLKSLWKLLLKAGLFKALLKLLKSLWKLLLKA 40 A 10 15
35 pAntpHD(Pro50) RQIKIWFPNRRMKWKK 16 A 7 68
36 pAntp(44–58) QIKIWFQNRRMKWKK 15 A 6 69
37 Crot(27–39) KMDCRWRWKCCKK 13 A 4.8 70
38 Crot(27–39) derevative (1) MDCRWRWKCCKK 12 A 3.8 70
39 Crot(27–39) derevative (2) KCGCRWRWKCGCKK 14 A 5.7 70
40 CyLoP-1 CRWRWKCCKK 10 A 4.8 70
41 Inv3 TKRRITPKDVIDVRSVTTEINT 22 H 2 71
42 Inv5 AEKVDPVKLNLTLSAAAEALTGLGDK 26 H -1 72
43 Inv3.5 TKRRITPKDVIDVRSVTTKINT 22 H 4 72
44 Inv3.10 HHHHHHTKRRITPKDVIDVRSVTTEINT 28 H 2.6 72
45 ARF(1–22) MVRRFLVTLRIRRACGPPRVRV 22 A 6.9 73
46 Cyt C 77–101 GTKMIFVGIKKKEERADLIAYLKKA 25 A 4 74
47 hLF peptide KCFQWQRNMRKVRGPPVSCIKR 22 A 6.9 48
48 Glu-Oct-6 EEEAAGRKRKKRT 13 A 3 75
49 M511 FLGKKFKKYFLQLLK 15 A 5 76
50 G53-4 FLIFIRVICIVIAKLKANLMCKT 23 H 3.9 76
51 M591 YIVLRRRRKRVNTKRS 16 A 8 76
52 E162 KTVLLRKLLKLLVRKI 16 A 6 76
53 E165 LLKKRKVVRLIKFLLK 16 A 7 76
54 M867 KKICTRKPRFMSAWAQ 16 A 4.9 76
55 MG2d GIGKFLHSAKKWGKAFVGQIMNC 23 H 4 77

aC: cationic, A: amphipathic, H: hydrophobic.