Figure 3.
Comparison of AAV6- and AAV6.2FF-Mediated Transgene Expression 24 hr Post-AAV Delivery
Albino C57BL/6 mice (n = 4 mice/group) received 1 × 1011 vg by intramuscular injection or intranasal delivery. (A) Quantification of luciferase expression in the muscle and lung 24 hr following intramuscular or intranasal delivery, respectively (n = 4/group). Data are expressed as mean ± SD. Multiple t tests compared AAV6.2FF-mediated luciferase expression with AAV6. Representative images illustrating the pattern and intensity of luciferase expression in the muscle (B) and the lungs (C).