Table 1.
Formulations | Particle size (d, nm) | Zeta potential (mV) | PDI | EE% of DOX |
---|---|---|---|---|
Blank DQAsomes | 71.10±3.1 | 35.3±1.4 | 0.221±0.02 | – |
DQAsomes | 87.27±4.2 | 30.8±3.4 | 0.191±0.05 | 57.8±3.7 |
PS-DQAsomes | 104.1±3.4 | 14.2±3.6 | 0.171±0.03 | 50.22±4.5 |
HPS-DQAsomes | 112.7±3.3 | 12.7±2.8 | 0.168±0.02 | 53.44±3.8 |
Abbreviations: DOX, doxorubicin; DQA, dequalinium; EE, encapsulation efficiency; HPS, HER-2 peptide-PEG2000-Schiff base; PDI, polydispersity index.