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Cell cytotoxicity of different formulations against different cell lines
| Formulations | IC50 (μg/mL)
|
RI | RF | |
|---|---|---|---|---|
| MCF-7 | MCF-7/ADR | |||
| DOX | 16.8 | 395.6 | 23.55 | 1.00 |
| DQAsomes | 7.26 | 52.3 | 7.20 | 3.27 |
| PS-DQAsomes | 8.93 | 63.4 | 7.10 | 3.32 |
| HPS-DQAsomes | 6.51 | 35.6 | 5.47 | 4.31 |
Abbreviations: DOX, doxorubicin; DQA, dequalinium; HPS, HER-2 peptide-PEG2000-Schiff base; IC50, half maximal inhibitory concentration; RF, resistance factor; RI, resistance index.
