Table 2.
Significantly enriched GO terms and KEGG pathways of DEGs
| Category | Term | Description | Count | P-value |
|---|---|---|---|---|
| BP term | GO:0007062 | Sister chromatid cohesion | 23 | 4.30E–15 |
| BP term | GO:0007018 | Microtubule-based movement | 11 | 2.59E–05 |
| BP term | GO:0031145 | Anaphase-promoting complex-dependent catabolic process | 10 | 1.24E–04 |
| BP term | GO:0030198 | ECM organization | 14 | 1.03E–03 |
| CC term | GO:0000777 | Condensed chromosome kinetochore | 23 | 6.49E–17 |
| CC term | GO:0000776 | Kinetochore | 17 | 7.09E–11 |
| CC term | GO:0005819 | Spindle | 14 | 6.63E–06 |
| CC term | GO:0005874 | Microtubule | 19 | 5.31E–04 |
| MF term | GO:0008017 | Microtubule binding | 20 | 7.71E–07 |
| MF term | GO:0003777 | Microtubule motor activity | 11 | 2.27E–05 |
| MF term | GO:0001077 | Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 15 | 1.90E–03 |
| MF term | GO:0016887 | ATPase activity | 12 | 5.11E–03 |
| KEGG pathway | hsa05222 | Small cell lung cancer | 11 | 1.76E–04 |
| KEGG pathway | hsa05200 | Pathways in cancer | 26 | 1.95E–04 |
| KEGG pathway | hsa04512 | ECM–receptor interaction | 11 | 2.14E–04 |
Abbreviations: BP, biological process; CC, cellular component; DEG, differentially expressed gene; ECM, extracellular matrix; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; MF, molecular function.