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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Biomaterials. 2018 Apr 4;178:496–503. doi: 10.1016/j.biomaterials.2018.03.060

Scheme 1. Strategy for a photopolymerized thioester exchange hydrogel.

Scheme 1

When exposed to light in the presence of a photoinitiator, a multifunctional thiol and bifunctional alkene species react through a thiol-ene photoclick reaction. Excess thiols present in the network react with backbone thioesters in a thioester exchange reaction.