Levels of antigen-specific IgG1, IgG2, IgG3, IgM and IgE antibody isotypes in the sera of macaques. The levels of antigen-specific IgG1, IgG2, IgG3, IgM and IgE antibody isotypes were measured using an ELISA. The variables are mean ± S.D. n=10 macaques per group *P≤0.01 in comparison with the AL019 (alum plus glucopyranosyl lipid adjuvant-stable emulsion) group as analyzed by a Kruskal-Wallis test followed by Bonferroni correction for multiple tests.