Table 2.
CC expression of the studied genes regarding clinical variables and development into eRBs and TQ + GQs
| eRB | TQ + GQ | ||||
|---|---|---|---|---|---|
| p | OR (95% CI) | p | OR (95% CI) | ||
| TNFAIP6 | Age | 0.790 | 0.996 (0.965, 1.028) | 0.178 | 0.979 (0.948, 1.010) |
| BMI | 0.837 | 1.005 (0.957, 1.055) | 0.324 | 1.025 (0.976, 1.075) | |
| AMH | 0.195 | 1.045 (0.977, 1.118) | 0.043* | 1.083 (1.003, 1.169) | |
| aFollicle size (large) | < 0.001** | 2.146 (1.760, 2.617) | < 0.001** | 1.877 (1.512, 2.329) | |
| TNFAIP6 | 0.438 | 1.001 (0.997, 1.005) | 0.081 | 0.988 (0.974, 1.002) | |
| PTGS2 | Age | 0.817 | 0.996 (0.966, 1.027) | 0.179 | 0.979 (0.950, 1.010) |
| BMI | 0.976 | 1.001 (0.953, 1.051) | 0.435 | 1.019 (0.971, 1.070) | |
| AMH | 0.214 | 1.043 (0.975, 1.116) | 0.060 | 1.076 (0.997, 1.160) | |
| aFollicle size (large) | < 0.001** | 2.147 (1.760, 2.618) | < 0.001** | 1.863 (1.503, 2.308) | |
| PTGS2 | 0.439 | 0.966 (0.887, 1.054) | 0.670 | 0.978 (0.881, 1.085) | |
| PTX3 | Age | 0.873 | 0.997 (0.966, 1.029) | 0.084 | 0.973 (0.943, 1.004) |
| BMI | 0.831 | 0.995 (0.948, 1.044) | 0.492 | 1.017 (0.969, 1.068) | |
| AMH | 0.149 | 1.051 (0.982, 1.126) | 0.026* | 1.089 (1.010, 1.174) | |
| aFollicle size (large) | < 0.001** | 2.162 (1.751, 2.671) | < 0.001** | 1.880 (1.506, 2.346) | |
| PTX3 | 0.720 | 0.698 (0.097, 4.998) | 0.847 | 0.831 (0.126, 5.446) | |
| HAS2 | Age | 0.831 | 0.997 (0.967, 1.028) | 0.147 | 0.978 (0.949, 1.008) |
| BMI | 0.982 | 1.001 (0.954, 1.050) | 0.401 | 1.021 (0.973, 1.070) | |
| AMH | 0.163 | 1.048 (0.981, 1.120) | 0.037* | 1.081 (1.005, 1.163) | |
| aFollicle size (large) | < 0.001** | 2.120 (1.741, 2.582) | < 0.001** | 1.859 (1.504, 2.297) | |
| HAS2 | 0.511 | 0.995 (0.982, 1.009) | 0.043* | 0.955 (0.913, 0.998) | |
| GDF9 | Age | 0.785 | 0.995 (0.960, 1.031) | 0.208 | 0.976 (0.939, 1.014) |
| BMI | 0.715 | 0.990 (0.937, 1.045) | 0.348 | 1.027 (0.971, 1.085) | |
| AMH | 0.103 | 1.078 (0.985, 1.180) | 0.067 | 1.088 (0.994, 1.190) | |
| aFollicle size (large) | < 0.001** | 2.145 (1.683, 2.734) | < 0.001** | 1.913 (1.461, 2.505) | |
| GDF9 | 0.912 | 1.001 (0.987, 1.015) | 0.049* | 0.975 (0.952, 0.999) | |
(Studied genes are: tumour necrosis factor alpha induced protein 6 (TNFAIP6), prostaglandin-endoperoxide synthase 2 (PTGS2), hyaluronan synthase 2 (HAS2), pentraxin-related protein 3 (PTX3) and growth differentiation factor 9 (GDF9)). Embryos reaching blastocyst stage (eRB); top (TQ) or good quality (GQ) blastocysts
*p < 0.05; **p < 0.01
aSmall follicular size was selected as a reference category