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. 2018 Jul 21;24(27):2949–2973. doi: 10.3748/wjg.v24.i27.2949

Table 4.

A list of representative miRNAs isolated from exosomes in biological samples from colorectal cancer patients or cell lines that are of prognostic value

miRNA Method of detection Type of samples Tumor stage Ref.
miR-17-92a miRNA microarray Tumor specimens IV [78]
miR-19a miRNA microarray Tumor specimens IV [78]
let-7a qRT-PCR Serum I, II, IIIa, IIIb, IV [214]
miR-21 qRT-PCR and miRNA microarray Serum; plasma I, II, IIIa, IIIb, IV [214]
miR-23a qRT-PCR Serum I, II, IIIa, IIIb, IV [214]
miR-150 qRT-PCR Serum I, II, IIIa, IIIb, IV [214]
miR-203 qRT-PCR Serum I, II, III, IV [215]
miR-223 qRT-PCR Serum I, II, IIIa, IIIb, IV [214]
miR-1246 qRT-PCR Serum I, II, IIIa, IIIb, IV [214]
miR-1229 qRT-PCR Serum I, II, IIIa, IIIb, IV [214]
miR-548c-5p miRNA microarray and qRT-PCR Serum (downregulated) I, II, IIIa, IIIb, IV [216]
miR-638 miRNA microarray and qRT-PCR Serum (downregulated) I, II, IIIa, IIIb, IV [216]
miR-5787 miRNA microarray and qRT-PCR Serum (downregulated) I, II, IIIa, IIIb, IV [216]
miR-8075 miRNA microarray and qRT-PCR Serum (downregulated) I, II, IIIa, IIIb, IV [216]
miR-6869-5p miRNA microarray and qRT-PCR Serum (downregulated) I, II, IIIa, IIIb, IV [216]
miR-486-5p miRNA microarray and qRT-PCR Serum (upregulated) I, II, IIIa, IIIb, IV [216]
miR-3180-5p miRNA microarray and qRT-PCR Serum (upregulated) I, II, IIIa, IIIb, IV [216]
miR-96-5p and miR-149 qRT-PCR Plasma III [217]
miR-100 qRT-PCR Cell lines (DKO-1, Dks-8, DLD-1) [218]
miR-192 qRT-PCR Cell lines (HCT-15, SW480, WiDr) [219]
miR-210 qRT-PCR Cell line (HCT-8) [220]
miR-221 qRT-PCR Cell lines (HCT-15, SW480, WiDr) [219]
miR-379 qRT-PCR Cell lines (HCT-116, HT-29) [221]