Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 16;9:773. doi: 10.3389/fphar.2018.00773

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Youn, Park, Kim, Jung, Kang, Lim, Song, Kwak and Um.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of BBR on BPH-related factors after ERK inhibition in TP-treated RWPE-1 cells. The relative protein expressions of (A) p-ERK, p-JNk, p-p38 and (B) 5AR after U0126 co-treatment were analyzed by a Western blot analysis. (C) Relative protein expressions of t-ERK and 5AR after siERK1/2 co-treatment were analyzed by a Western blot analysis. Values are mean ± SD of three or more separate experiments. ^∗P < 0.05 when compared to TP. The protein expressions differences of 5AR were normalized to GAPDH. The protein expressions differences of p-ERK, p-JNK, and p-p38 were normalized to total ERK, total JNK, and total p38, respectively. (D) Representative photomicrographs of EdU assay of ERK-inhibited RWPE-1 cells are shown. IF analysis of Ki67 (green) merged with DAPI (blue) was performed. NC, normal control group; TP, TP-treated group; BBR, BBR-treated group.