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. 2018 Jul 16;9:735. doi: 10.3389/fphar.2018.00735

Figure 1.

Figure 1

A schematic summary of recent advances in the development of exosome delivery system. Isolation: New exosome isolation method utilizing transferrin-coated superparamagnetic (M-Tf) nanoparticles (Qi et al., 2016). Drug loading: A optically reversible protein-protein interaction (EXPLORs) technology to load proteins into exosomes (Yim et al., 2016). Delivery: Summary of three recent advances in facilitating the delivery of exosomes to tumors (Qi et al., 2016; Bellavia et al., 2017; Kamerkar et al., 2017). CML, chronic myeloid leukaemia; CRY2, cryptochrome 2; CIBN, truncated cryptochrome-interacting basic-helix-loop-helix1; Lamp2b, lysosome-associated membrane protein 2; IL-3, interleukin 3.