Table 2. Characteristics of the study subjects not on renal replacement therapy.
| eGFR (mL/min/1.73 m2) |
|||||
|---|---|---|---|---|---|
| ≤ 45 | 45–59 | 60–89 | ≥ 90 | p-trend | |
| (n = 431) | (n = 571) | (n = 1306) | (n = 435) | ||
| Age, mean years ± SD | 80.9 ± 10.9 | 78 ± 10.4 | 72.5 ± 12.9 | 66.7 ± 15.4 | < .0001 |
| Female, n (%) | 229 (53.1) | 265 (46.4) | 572 (43.8) | 210 (48.3) | 0.25 |
| Comorbidities, n (%) | |||||
| Hypertension | 351 (82.4) | 433 (76.6) | 917 (70.8) | 272 (63.6) | < .0001 |
| Diabetes | 152 (35.8) | 141 (24.7) | 329 (25.3) | 104 (24.3) | 0.001 |
| Myocardial infarction | 45 (10.6) | 39 (6.9) | 61 (4.7) | 20 (4.6) | < .0001 |
| Atrial fibrillation | 135 (31.8) | 145 (25.6) | 226 (17.4) | 53 (12.2) | < .0001 |
| Dyslipidemia | 136 (33.8) | 210 (38.9) | 462 (37.4) | 143 (35) | 0.67 |
| Previous stroke, n (%) | 126 (29.6) | 176 (30.9) | 322 (24.7) | 82 (18.9) | < .0001 |
| Smoking status, n (%) | < .0001 | ||||
| Never | 283 (74.3) | 364 (70.8) | 751 (62.7) | 236 (59.2) | |
| Ex | 52 (13.7) | 74 (14.4) | 153 (12.8) | 46 (11.5) | |
| Current | 46 (12.1) | 76 (14.8) | 293 (24.5) | 117 (29.3) | |
| SBP, mean mmHg ± SD | 157.2 ± 35.1 | 160.3 ± 32.8 | 163.7 ± 32.1 | 162.4 ± 33.4 | 0.05 |
| DBP, mean mmHg ± SD | 83.1 ± 20.9 | 86.9 ± 21.4 | 90.5 ± 19.8 | 90.9 ± 19.4 | < .0001 |
| Japan Coma Scale, n (%) | 0.03 | ||||
| 0 | 140 (32.6) | 258 (45.2) | 651 (50) | 192 (44.4) | |
| 1–3 (1-digit) | 127 (29.6) | 158 (27.7) | 314 (24.1) | 94 (21.8) | |
| 10–30 (2-digit) | 58 (13.5) | 77 (13.5) | 164 (12.6) | 58 (13.4) | |
| 100–300 (3-digit) | 104 (24.2) | 78 (13.7) | 174 (13.4) | 88 (20.4) | |
| eGFR, mean mL/min/1.73 m2 ± SD | 33.4 ± 9.5 | 53.4 ± 4.1 | 73.7 ± 8.4 | 108.5 ± 21.2 | < .0001 |
| Admission mRS, n (%) | < .0001 | ||||
| 0 | 205 (47.6) | 316 (55.3) | 872 (66.8) | 310 (71.3) | |
| 1 | 59 (13.7) | 79 (13.8) | 152 (11.6) | 32 (7.4) | |
| 2 | 36 (8.4) | 41 (7.2) | 79 (6.1) | 17 (3.9) | |
| 3 | 59 (13.7) | 59 (10.3) | 80 (6.1) | 14 (3.2) | |
| 4 | 58 (13.5) | 60 (10.5) | 93 (7.1) | 32 (7.4) | |
| 5 | 14 (3.3) | 16 (2.8) | 30 (2.3) | 30 (6.9) | |
| Intervention/surgery, n (%) | 29 (6.8) | 44 (7.7) | 137 (10.5) | 86 (19.8) | < .0001 |
| tPA, n (%) | 11 (2.6) | 22 (3.9) | 38 (2.9) | 6 (1.4) | 0.31 |
| Onset-death/discharge days, median (IQR) | 24 (12–51) | 27 (13–48) | 25 (13–45) | 25 (13–46) | 0.36 |
| Final diagnosis, n (%) | < .0001 | ||||
| Ischemic | 322 (74.7) | 418 (73.2) | 850 (65.1) | 213 (49) | |
| Haemorrhagic | 108 (25.1) | 153 (26.8) | 455 (34.8) | 219 (50.3) | |
SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; mRS, modified Rankin Scale; tPA, tissue plasminogen activator