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SD-FRE improved glucose metabolism in KK-Ay mice. FBG levels (A) and body weight (B) of KK-Ay mice at 0 and 4 weeks of SD-FRE treatment. Blood glucose levels (C) and AUC of glucose (D) during OGTT. Serum insulin level (E) and values of HOMA-IR in each group (F). Data are mean ± SEM (n = 8). +++p < 0.001 vs. NC group, ∗∗p < 0.01, ∗∗∗p < 0.001 vs. DC group.
