Fig. 2.

Intact optic nerves are essential for light-triggered anagen entry. (A) Effect of optic nerve crushing. Premature anagen induction by blue light was completely prohibited after optic nerves were disrupted. *P < 0.05 (n = 10). (B) Roles of rods and cones. Anagen entry could still be induced by light in Gnat1^−/−; Gnat2^cpfl3/cpfl3 mice whose signaling from rods and cones was inactivated, but the area with anagen induction was reduced in comparison with wild-type mice. *P < 0.05 (n = 10).