Figure 1.

Pedigree and clinical photos of family 1. (A) Pedigree of family 1. The plus symbol (+) indicates members recruited for this study. The proband is indicated with a black arrow. The question mark (?) indicates that the affection status of this individual cannot be determined due to full-coverage prosthetics on all teeth. (B–F) Clinical photo of the proband (II:1) at age 19 y. Generalized hypoplastic enamel in all teeth can be seen, and characteristic horizontal hypoplastic grooves can be noticed in the buccal surfaces or mandibular premolars. (G) Panoramic radiograph of the proband at age 19 y.