Figure 4.

OS and DFS for FGFR1 gene amplification determined by FISH. (A, B) FGFR1 amplification is not associated with prognosis. (C, D) When restricting analysis to the HPV-negative group only (n=30), there is still no association with OS (C) or DFS (D). (E, F) When restricting the analysis to smokers (n=53), there is no association with OS (E) or DFS (F). Abbreviations: OS, overall survival; DFS, disease-free survival; FGFR1, fibroblast growth factor receptor 1; FISH, fluorescence in situ hybridization; HPV, human papillomavirus.