Table 4.
The 10 most common causes of death among decedents with systemic lupus erythematosus (SLE) in the Swedish Lupus Linkage (SLINK) population for whom SLE was not reported as a cause of death in the Cause of Death Register, and number of non-SLE deathsa for each cause of death in SLINK, Sweden, 2001-2013b
| Rank | ICD-10 Codec | Definition | Total Deaths, No. (%) | Mean (SD)b Age at Death, y | Median (IQR) Age at Death, y | |||
|---|---|---|---|---|---|---|---|---|
| SLE Deaths in SLINK for Which SLE Was Not Reported in Death Records (n = 1071) | Non-SLE Deaths in SLINK (n = 3308) | SLE Deaths in SLINK for Which SLE Was Not Reported in Death Records (n = 1071) | Non-SLE Deaths in SLINK (n = 3308) | SLE Deaths in SLINK for Which SLE Was Not Reported in Death Records (n = 1071) | Non-SLE Deaths in SLINK (n = 3308) | |||
| 1 | I50 | Heart failure | 243 (23) | 646 (20) | 78 (10) | 83 (8) | 79 (71-86) | 84 (80-88) |
| 2 | I25 | Chronic ischemic heart disease | 167 (16) | 435 (13) | 75 (10) | 79 (9) | 76 (68-83) | 81 (74-86) |
| 3 | I21 | Acute myocardial infarction | 134 (13) | 349 (11) | 75 (11) | 77 (10) | 77 (69-83) | 79 (72-85) |
| 4 | J18 | Pneumonia, unspecified organism | 121 (11) | 333 (10) | 75 (12) | 80 (10) | 78 (67-83) | 83 (76-87) |
| 5 | I70 | Atherosclerosis | 109 (10) | 296 (9) | 76 (9.5) | 81 (8) | 77 (70-83) | 82 (76-87) |
| 6 | C79 | Secondary malignant neoplasm of other and unspecified sites | 86 (8) | 337 (10) | 68 (11) | 71 (11) | 69 (62-75) | 72 (64-79) |
| 7 | C34 | Malignant neoplasm of bronchus and lung | 85 (8) | 182 (6) | 68 (10) | 71 (9) | 69 (61-76) | 71 (65-78) |
| 8 | J44 | Other chronic obstructive pulmonary disease | 82 (8) | 261 (8) | 75 (9) | 77 (8) | 77 (70-80) | 78 (72-84) |
| 9 | I48 | Myocarditis in diseases classified elsewhere | 79 (7) | 269 (8) | 79 (10) | 83 (7) | 79 (74-87) | 84 (79-88) |
| 10 | A41 | Other sepsis | 71 (7) | 110 (3) | 72 (13) | 76 (11) | 76 (65-81) | 78 (70-84) |
Abbreviations: ICD-10, International Classification of Diseases, 10th Revision; IQR, interquartile range.
a Non-SLE deaths refer to decedents from the general population comparators group in SLINK. The general population comparators group in SLINK comprises people without SLE who were matched 5:1 to SLE cases on birth year, sex, and county of residence at the time each case was diagnosed.
c International Classification of Diseases, 10th Revision.21