. 2018 May 30;25(9):R467–R478. doi: 10.1530/ERC-18-0068
This work is licensed under a Table 2.
Number and percentage of patients pertaining to each subtype with an alteration in the specified spliceosome component genes.
| SF3B1 | SF3B3 | SRSF1 | SRSF2 | SRSF3 | SRSF4 | RBFOX2 | ESRP1 | RBM47 | LIN28A | |
|---|---|---|---|---|---|---|---|---|---|---|
| Basaln = 391 | 12 (3.07) | 10 (2.56) | 11 (2.81) | 22 (5.63) | 15 (3.84) | 6 (1.53) | 5 (1.28) | 84 (21.48) | 13 (3.32) | 1 (0.26) |
| Her2n = 287 | 9 (3.14) | 3 (1.05) | 39 (13.59) | 25 (8.71) | 2 (0.70) | 1 (0.35) | 2 (0.70) | 99 (34.49) | 6 (2.09) | 1 (0.35) |
| Luminal An = 909 | 40 (4.40) | 17 (1.87) | 31 (3.41) | 26 (2.86) | 5 (0.55) | 2 (0.22) | 2 (0.22) | 103 (11.33) | 5 (0.55) | 3 (0.33) |
| Luminal Bn = 590 | 19 (3.22) | 5 (0.85) | 99 (16.78) | 50 (8.47) | 3 (0.51) | 2 (0.34) | 4 (0.68) | 159 (26.95) | 2 (0.34) | 1 (0.17) |
| Normal liken = 179 | 4 (2.23) | 3 (1.68) | 10 (5.59) | 7 (3.91) | 0 (0.00) | 1 (0.56) | 0 (0.00) | 23 (12.85) | 1 (0.56) | 0 (0.00) |
Data were derived from METABRIC and TCGA samples with available PAM50 subtype scores (n = 2363). Percentages in brackets.