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. 2018 Jul 23;6:64. doi: 10.1186/s40478-018-0558-5

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Pearson correlation plot with false discovery rate (fdr). Color and size of the circles indicate the strength of the Pearson correlation coefficient (for Pearson correlation coefficient, p-value and numerical fdr see Additional file 3: Table S3a-c), asterisks indicate the false discovery rate (* < 20%, ** < 10%, *** < 5%), X indicates no correlation. Correlations between the same test at baseline and last visit were performed for 20 cases with at least one follow up visit. Thal stage GVD* indicates that we utilized a staging system for GVD adapted from Thal et al., 2011 [44]