Table 1.
Baseline clinical data and biomarker concentrations in ischemic stroke patients and their correlations to total BNIS score at 7‐year follow‐up
| Whole sample, n = 268 | Stroke <50 years, n = 67 | |||||
|---|---|---|---|---|---|---|
| Correlation coefficient (r) | 95% CI for r | Correlation coefficient (r) | 95% CI for r | |||
| Age at index stroke, years, mean (SD) | 55 (11) | −.28 | −0.39, −0.17 | 40 (8) | .04 | −0.20, 0.28 |
| Age <65 years at index stroke, n (%) | 223 (83%) | −.30 | −0.41, −0.19 | NA | NA | |
| Male sex, n (%) | 169 (63%) | −.05 | −0.17, 0.07 | 32 (48%) | −.10 | −0.33, 0.14 |
| Education | ||||||
| 1 Low level, n (%) | 83 (31%) | .38 | 0.27, 0.48 | 13 (20%) | .37 | 0.14, 0.56 |
| 2 Medium level, n (%) | 103 (38%) | 28 (42%) | ||||
| 3 High level, n (%) | 77 (29%) | 25 (37%) | ||||
| Hypertension, n (%) | 142 (53%) | −.14 | −0.26, −0.02 | 17 (25%) | −.04 | −0.28, 0.20 |
| Smoking, n (%) | 95 (35%) | −.07 | −0.19, 0.05 | 25 (37%) | −.17 | −0.39, 0.07 |
| Diabetes mellitus, n (%) | 45 (17%) | −.20 | −0.31, −0.08 | 11 (16%) | −.40 | −0.58, −0.18 |
| Hyperlipedemia, n (%) | 190 (71%) | −.09 | −0.21, 0.03 | 34 (51%) | −.07 | −0.31, 0.18 |
| SSS score, median (IQR) | 54 (47‐57) | .36 | 0.25, 0.46 | 54 (47‐58) | .67 | 0.51, 0.78 |
| Years from last stroke, median (IQR) | 7.3 (7.2‐7.5) | .25 | 0.14, 0.36 | 7.3 (7.2‐7.5) | .13 | −0.11, 0.36 |
| Fibrinogen, g/L, median (IQR) | 3.2 (2.8‐3.7) | −.22 | −0.33, −0.10 | 2.9 (2.5‐3.4) | −.35 | −0.55, −0.11 |
| VWF antigen, IU/dL, median (IQR) | 208.6 (164.6‐274.3) | −.18 | −0.30, −0.06 | 185.3 (150.5‐226.3) | −.17 | −0.40, 0.08 |
| t‐PA antigen, μg/L, median (IQR) | 11.2 (8.6‐14.4) | −.18 | −0.29, ‐0.06 | 9.6 (6.8‐11.9) | −.23 | −0.45, 0.02 |
BNIS, Barrow Neurological Institute Screen for Higher Cerebral Functions; SSS, Scandinavian Stroke Scale; VWF, von Willebrand factor; t‐PA, tissue‐type plasminogen activator; CI, confidence interval. Pearson correlation was used to calculate correlation to total BNIS score. Data are shown as median and interquartile range (IQR), mean and standard deviation (SD), or number (n) and percentage.