Table 4.

ALFSG Model Performance According to Hepatic Encephalopathy HE) Grade and ALF Etiology (Validation Cohort)

HE Grade	Etiology	SS %	Total Subjects	Actual Equals Predicted Outcome	% Correctly Predicted (SS or non-SS)	Model Incorrectly Predicts Spontaneous Survival†	Model Incorrectly Predicts Negative Outcome (Death or LT) ††
Mild	Favorable	85	209	135	64.6%	11(5.3%)	63 (30.1%)
Deep	Favorable	55	278	157	56.5%	10 (3.6%)	111 (39.9%)
Mild	Unfavorable	33	228	160	70.2%	0 (0.0%)	68 (29.8%)
Deep	Unfavorable	21	170	135	79.4%	0 (0%)	35 (20.6%)
Total			885*	587	66.3%	21 (2.4%)	277 (31.3%)

^*Predictor variables missing from 102/987 subjects leaving 885 for analysis.

^†Subjects in which the model incorrectly predicts spontaneous survival when death or LT occurs.

^††Subjects in which the model incorrectly predicts the negative outcome (death or LT) when spontaneous survival occurs.