Table 3.
Lipid Profiles and Inflammatory Markers During Hormone Administration in 74 Older Healthy Men
| Parameter | Group A | Group B | Group C | Group D | ANOVA |
|---|---|---|---|---|---|
| TC (mg/dL) | 175 ± 7.1 | 166 ± 6.3 | 158 ± 7.1 | 166 ± 5.0 | 0.34 |
| HDL-C (mg/dL) | 42 ± 3.5 | 37 ± 2.8 | 42 ± 3.3 | 42 ± 2.6 | 0.62 |
| LDL-C (mg/dL) | 100 ± 6.3 | 91 ± 4.3 | 84 ± 5.8 | 90 ± 4.5 | 0.018 a |
| Non-HDL-C (mg/dL) | 133 ± 6.7 | 128 ± 6.2 | 116 ± 7.2 | 124 ± 4.9 | 0.31 |
| Triglycerides (mg/dL) | 161 ± 16.7 | 187 ± 20.9 | 163 ± 16.9 | 168 ± 19.0 | 0.77 |
| Lp(a) (mg/dL) | 27.0 ± 6.3 | 23.3 ± 5.3 | 21.9 ± 4.4 | 16.8 ± 4.1 | 0.55 |
| ApoB (mg/dL) | 0.88 ± 0.044 | 0.84 ± 0.043 | 0.78 ± 0.049 | 0.82 ± 0.029 | 0.34 |
| Adiponectin (mg/dL) | 9840 ± 1190 | 6120 ± 616 | 7690 ± 650 | 8250 ± 980 | 0.039 b |
| HsCRP (mg/dL) | 0.36 ± 020 | 0.17 ± 0.05 | 0.076 ± 0.012 | 0.11 ± 004 | 0.16 |
| Leptin (ng/mL) | 14.6 ± 2.1 | 9.6 ± 1.9 | 6.8 ± 0.7 | 10.2 ± 1.9 | 0.023 c |
| Interleukin 6 (pg/mL) | 5.2 ± 2.1 | 3.8 ± 0.6 | 3.4 ± 0.4 | 3.9 ± 0.7 | 0.67 |
Data are shown as mean ± SEM. Boldface values denote ANOVA P < 0.05.
Post hoc contrasts:
a
Group A vs group C: P = 0.029.
b
Group A vs groups B, C, D jointly: P = 0.008.
c
Group A vs groups B, and C and D jointly: P = 0.02, group A vs group B; P = 0.005.