Figure 3.

Relationships with flow reduction from aortic stenosis. For the 13 subjects with successful paired assessments before and after transcatheter aortic valve implantation, we can estimate the flow reduction due to the stenotic aortic valve since systemic vascular resistance during systolic ejection remains constant during peak dobutamine (see Supplementary material online). The stress aortic valve index, equal to the aortic/left ventricular pressure ratio during systolic ejection, shows the best correlation (solid red lines denote 95% confidence ellipses), with stress assessments performing better than resting assessments and unitless ratios performing better than their corresponding absolute gradients with intermediate performance for the aortic valve area.