Table 1.
Descriptive patient data collected prior to transplantation
| Parameter | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
|---|---|---|---|---|
| Gender | Female | Male | Male | Female |
| Age (years) | 53 | 47 | 59 | 44 |
| Weight (kg) | 72 | 99 | 79 | 72 |
| Height (cm) | 174 | 189 | 179 | 172 |
| BMI (kg/m2) | 23.8 | 27.7 | 24.7 | 24.3 |
| Diabetes duration (years) | 41 | 30 | 30 | 39 |
| Retinopathy | Discrete | Discrete | Discrete | Discrete |
| Treatment regimen | Injections | Pump | Pump | Injections |
| HbA1c before run‐in (mmol/mol, DCCT %) | 73 (8.8) | 68 (8.4) | 66 (8.2) | 63 (7.9) |
| HbA1c after run‐in (mmol/mol, DCCT %) | 62 (7.8) | 71 (8.6) | 62 (7.8) | 63 (7.9) |
| Total insulin doses (U/24 h) | 36 | 54 | 46 | 30 |
| Insulin doses (U/24 h/kg) | 0.5 | 0.56 | 0.58 | 0.42 |
| Exercise | 3 times weekly | 2‐3 times weekly | 2‐3 times weekly | 2‐3 times weekly |
| Hypoglycemia unawareness | No | No | No | No |
| Other drugs | Levothyroxine | Statins | Levothyroxine | ‐ |
| Total number of islets (IEQ) transplanted and islet purity (%) |
155 000 96% |
180 000 81% |
180 000, 180 000 86%, 89% |
180 000 92% |
| Number of islets transplanted (IEQ/kg BW) | 2150 | 1800 | 4600 | 2500 |
Apart from discrete retinopathy none of the patients had any diabetes‐related long‐term complications. IEQ, islet equivalents.