Table 5.

Within‐trait subgroup effects during scanning in PWS

Brain region	Number of voxels	Z statistic	X	Y	Z	DYS	FLU
Right subcortical grey matter	1,413
Right caudate nucleus		3.24	12	4	8	0	+
Right putamen/pallidum		3.76	20	0	−12	−	+
Right putamen/pallidum		2.93	22	−2	−2	+	+
Right planum polare*		2.88	44	−4	−16	−	0
Right superior temporal sulcus		3.51	52	−10	−16	−	+
Posterior medial‐frontal cortex	1,947
Right mid‐cingulate gyrus*		3.67	6	−4	44	−	−
Left mid‐cingulate gyrus*		3.66	−4	−4	44	−	+
Right cingulate sulcus		3.91	8	−8	46	−	−
Left temporo‐occipital cortex	1,041
Left planum polare*		3.31	−46	−6	−10	−	+
Left inferior temporal gyrus		3.81	−54	−40	−24	−	+
Left lateral cerebellum, lobule VI		2.81	−38	−50	−30	0	+
Left inferior temporal cortex, fusiform		3.61	−46	−54	−18	+	+
Left lateral occipital cortex		3.61	−44	−72	−12	+	+
Posterior medial cortex	1,638
Right retrosplenial cortex		3.44	8	−46	22	−	−
Left precuneus		3.23	−2	−66	22	+	+
Right medial occipital cortex		3.84	2	−86	30	−	−
Right occipital pole		4.48	10	−96	28	+	+

Regions where there was significantly reduced activity for the DYS relative to FLU subgroups averaged across speaking tasks (Z > 2.3, p < .05 corrected). There were no regions where there was significantly more activity in the DYS relative to the FLU subgroup. The right‐most columns indicate the direction of subgroup averages across both speaking tasks relative to the baseline for the peak voxel reported (“−” = negative; “+” = positive, “0” = −1 < Z < 1). See the legend to Table 3 for further details.