Table 1.
Studies reporting the outcomes following metal-on-metal hip arthroplasty revision surgery performed for ARMD
| A | B | C | D | E | F | G | H | I | J |
|---|---|---|---|---|---|---|---|---|---|
| Grammatopoulos et al. (2009) | 16 R | 100% (16) |
51.3 (20–71) |
1.6a (0.01–6.7) |
3.0a (0.8–7.2) |
50% (8) |
38% (6) |
Dislocation ± ARMD recurrence (4) Loose cup (2) |
Mean OHS 20.9 |
| Rajpura et al. (2011) | 11 R | 36% (4) |
53.5 (22–67) |
3.8 (1.3–7.3) |
1.8 (1.0–3.3) |
18% (2) |
18% (2) |
ARMD recurrence (2) | Mean OHS 35.3 |
| De Smet et al. (2011) | 48 R | 61% (NS)a |
52.5 (18–71) |
2.7 (0.3–8.4) |
3.3a (0.3–10.1) |
≤ 23% (11)a |
≤ 13% (6) * |
Loose cup or stem (2) Infection (2) ARMD recurrence (1) |
Mean HHS 93.1a |
| Ebreo et al. (2011) | 42 R + T |
55% (23) |
Median 61 (NS) |
4.7a (1.3–7.8) |
2.2a (1.2–4.0) |
≤ 10% (4)a |
≤ 2% (1)a |
Infection (1) | Mean OHS 23.7a |
| Liddle et al. (2013) | 32 R | 81% (26) |
57.7 (25–74) |
4.3 (0.9–10.9) |
Median 2.5 (1.0–4.5)a |
≤ 6% | ≤ 6% | Dislocation (1) ARMD recurrence with loose cup (1) |
Median OHS 36.5a |
| Su and Su (2013) | 13 R | 85% (11) |
NS | NS | 2.3a (0.7–6.7) |
≤ 15% (2)a |
≤ 15% (2)a |
Infection (2) | Mean HHS 96.4 |
| Munro et al. (2014) | 19 T | 37% (NS)a |
57.5 (46–76) |
2.8a (0.6–4.9) |
2.1a (0.8–4.0) |
68% (13) |
21% (4) |
Dislocation and/or loose cup (3) ARMD recurrence (1) |
Mean WOMAC (pain) 78 (function) 83 |
| Pritchett (2014) | 90 R | 48% (43) |
49.8 (32–71) |
2.8 (1.3–4.9) |
5.1 (3.0–9.8) |
4% (4) |
3% (3) |
ARMD recurrence (1) Infection (1) Loose cup (1) |
Mean HHS 93.2 |
| Matharu et al. (2014b) | 46 R 18 T |
72% (46) |
57.8 (31–79) |
5.5 (1.1–13.8) |
4.5 (1.0–14.6) |
20% (13) |
13% (8) |
Dislocation (2) ARMD recurrence (2) |
Median OHS 39 |
| Norris et al. (2014) | 35 R | 71% (25) |
58.0 (30–76) |
4.3 (1.5–9.6) |
NS | NS |
NS | NS | Mean OHS 33 |
| Cip et al. (2015) | 20 T | 47% (NS)a |
49.6a (21–61) |
4.6a (2.7–6.7) |
2.3 (1.5–3.1) |
10% (2) |
5% (1) |
Infection (1) | Mean HHS 85.1 |
| Stryker et al. (2015) | 58 T | 65% (NS)a |
60.0a (17–84) |
3.9a (0.1–9.5) |
1.2a (0–10.2) |
20% (23) |
16% (18) |
Infection (7) Loose cup or stem (6) Dislocation (4) |
NS |
| Lainiala et al. (2015) | 49 R 166 T |
60% (130) |
62.1 (SD 10.1) |
4.7 (SD 1.3) |
2.3 (1.0–NS) |
5% (11) |
3% (6) |
Dislocation (4) Infection (1) |
Median OHS 40 |
| van Lingen et al. (2015) | 38 T | 69% (NS)a |
63.0a (44–75) |
Median 3.7 (1.0–6.5)a |
3.1a (2.1–4.7) |
24% (9) |
8% (3) |
Dislocation (3) | Mean HOOS 61.9a |
| Liow et al. (2016) | 25 R 77 T |
36% (35) |
62.0 (41–85) |
5.1 (1.4–18.3) |
2.5 (2.2–4.3) |
14% (14) |
7% (7) |
ARMD recurrence (3) Dislocation (2) Loose cup (2) |
Mean HSS 75.6 |
| Matharu et al. (2017b)b | 16 R | 100% (16) |
51.3 (20–71) |
1.6a (0.01–6.7) |
Median 10.3 (7–15)a |
69% (11) |
44% (7) |
Dislocation ± ARMD recurrence (5) Loose cup (2) |
Median OHS 21 |
NS = not stated, SD = standard deviation
A. Study author and year
B. Hips revised for ARMD (adverse reactions to metal debris)
R: Resurfacing arthroplasty
T: Total hip arthroplasty
C. Female hips, % (n)
D. Mean age (range) at revision in years
E. Mean time to revision (range) in years
F. Mean follow-up time after revision (range) in years
G. Frequency of complications, % (n)
H. Frequency of re-revision, % (n)
I. Main reasons for re-revision surgery, % (n)
j. Functional outcome: Functional outcome scoring systems: OHS (Oxford Hip Score) = 0–48 (48 best outcome) (Dawson et al. 1996, Murray et al. 2007); HHS (Harris Hip Score) = 0–100 (100 best outcome) (Harris 1969); HOOS (Hip disability and osteoarthritis outcome score) = 0–100 (100 best outcome) (Klassbo et al. 2003); WOMAC (Western Ontario and McMaster Universities Arthritis Index) = 0–100 (0 best out-come) (Bellamy et al. 1988).
Studies did not provide the relevant data specifically for the cohort of patients undergoing revision for adverse reactions to metal debris (but rather for the whole cohort of metal-on-metal hip arthroplasty revisions that they reported on).
Updated report on Grammatopoulos et al. (2009)