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. 2018 Jul 18;10:2105–2115. doi: 10.2147/CMAR.S168374

Table 2.

Diagnostic efficacy of MRI and 18F-FDG PET/CT in finding the malignancy in all patients

Feature Group
Sensitivity (%) Specificity (%) PPV NPV
Malignant fracture Benign fracture
Epidural mass formation 34/41 14/75 82.9 81.3 70.8 89.7
Convex posterior cortex 31/41 17/75 75.6 77.3 64.6 85.3
Pedicle enhancement 30/35 14/48 85.7 70.8 68.2 87.2
All three features 19/35 3/48 54.2 93.8 86.4 73.8
18F-FDG PET/CT 41/41 11/18 100.0 38.9 90.1 100.0

Notes: Values represent number of lesions showing the specified feature/number of lesions evaluated. Group assignment was based on final diagnosis as determined by biopsy or clinical follow-up.

Abbreviations: PPV, positive predictive value; NPV, negative predictive value; 18F-FDG, 2-[fluorine-18]-fluoro-2-deoxy-D-glucose; PET, positron emission tomography; CT, computed tomography.