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Nevirapine damages the mitochondria of the hepatocytes and the endothelium. A & B: degenerate mitochondrial (mostly the inner membrane) in the hepatocytes (arrows), and C: endothelial cells (arrows). D: degenerate mitochondria within the sinusoidal lumina (arrows). E: a mitochondrion within LSER inclusions (arrow). F: Mitochondria surrounded by extra membranes indicating the formation of what could be autophagosomes.
