Skip to main content
. 2018 Jul 23;13(7):e0201066. doi: 10.1371/journal.pone.0201066

Fig 5. Distribution of differentially methylated promoter regions in ME/CFS according to gene biotype.

Fig 5

In RnBeads package, promoters are defined as regions 1500 bp upstream of TSS and 500 bp downstream of TSS. Criteria for DMPs were: FDR ≤ 0.1 and mean difference > 0.05. The distribution of these DMPs according to the gene biotype: protein-coding genes and regulatory RNA genes including short non-coding RNAs (miRNAs, small nuclear RNAs, small nucleolar RNAs), long non-coding RNAs (including antisense RNAs and intergenic RNAs) and pseudogenes.