Table 2. Mass spectrometric identification of CTLH complex subunits co-purified with TAP-tagged Bicc1 MutD.
CTLH/GID subunit | Fold enrichment of peptides 1 | ||||
---|---|---|---|---|---|
Rank | Gene name | Name | Bicc1 WT | Bicc1 MutD | |
1 | GID7 | WDR26 | WD repeat-containing protein 26 | 110 | 31 |
49 | GID9 | MAEA1 | Macrophage erythroblast attacher | 42 | 5 |
71 | GID8 | TWA1 | Glucose-induced degradation protein 8 homolog | 38 | 4 |
166 | GID5 | ARMc8 | Armadillo repeat-containing protein 8 | 27 | 2 |
256 | GID1 | RanBP9 | Ran-binding protein 9 | 23 | 6 |
264 | MKLN1 | MKLN1 | Muskelin | 22 | 4 |
328 | GID2 | RMND5a | Required for meiotic nuclear division 5 homolog A | 20 | 1 |
110 | - | ANKS3 | Ankyrin repeat and SAM domain-containing protein 3 | 32 | 10 |
26 | - | CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, dihydroorotase | 50 | 46 |
37 | - | FASN | Fatty acid synthase | 46 | 49 |
1452 | - | ACACA | Acetyl-CoA-carboxylase alpha | 5 | 5 |
1 Data represent the total peptide counts from 2 experiments. The fold change was calculated by adding +1 to all counts.