Table 1. Human norovirus–positive fecal samples tested on 80 jejunal HIEs in study of human norovirus replication in HIEs.
| Genotype* | No. samples |
Mean norovirus RNA copies/μL |
Patient age group | Collection date† |
Storage condition‡ |
Outbreak or sporadic |
No. inactivated/ no. samples % |
||
|---|---|---|---|---|---|---|---|---|---|
| Capsid |
RdRp |
Years |
No. |
||||||
| GI.1 |
GI.P1 |
4 |
0.5–19.3 × 103 |
>18 |
4 |
2000 |
−70°C |
Sporadic |
0/4 (0) |
| GI.3 |
GI.P3 | 2 | 0.3–59.4 × 104 | 0–12 | 1 | 2013 Jul | −70°C | Sporadic | 0/4 (0) |
| >18 | 1 | 2005 | −70°C | Outbreak | |||||
| GI.Pd |
2 |
1.2–8.7 × 104 |
0–12 |
1 | 2015 Nov | −70°C | Sporadic | ||
| 1 |
2017 Feb |
−70°C |
Sporadic |
||||||
| GI.4 |
GI.P4 |
1 |
2.2 × 102 |
>18 |
1 |
2000 |
−70°C |
Outbreak |
0/1 (0) |
| GI.7 |
GI.P7 |
3 |
2.6–16.4 × 103 |
0–12 |
1 | 2010 Nov | −70°C | Sporadic | 0/3 (0) |
| 1 | 2014 Mar | −70°C | Sporadic | ||||||
| 1 |
2016 Dec |
−70°C |
Sporadic |
||||||
| GII.1 |
GII.Pg |
1 |
1.4 × 105 |
0–12 |
1 |
2017 May |
−70°C |
Sporadic |
1/1 (100) |
| GII.2 |
GII.P16 |
3 |
0.2–52.6 × 103 |
0–12 |
2 | 2017 Feb | −70°C | Sporadic | 1/2 (50) |
| 1 |
2017 Mar |
−70°C |
Sporadic |
0/1 (0) |
|||||
| GII.3 |
GII.P21 | 2 | 1.0–6.4 × 105 | 0–12 | 1 | 2012 Mar | −70°C | Sporadic | 0/1 (0) |
| 1 | 2015 May | −70°C | Sporadic | ||||||
| GII.P12 | 2 | 1.6–4.4 × 106 | 0–12 | 2 | 2012 Aug | −70°C | Sporadic | 1/2 (50) | |
| GII.P16 |
4 |
0.2–141.1 × 104 |
0–12 |
1 | 2012 Mar | −70°C | Sporadic | 0/4 (0) |
|
| 1 | 2012 Jun | −70°C | Sporadic | ||||||
| 1 | 2015 Oct | −70°C | Sporadic | ||||||
| 1 |
2016 Dec |
−70°C |
Sporadic |
||||||
| GII.4 Den Haag |
GII.P4 Den Haag |
3 |
1.3–161.6 × 104 |
>18 | 1 | 2010 May | 4°C | Outbreak | 0/1 (0) |
| 0–12 |
1 | 2013 Jun | −70°C | Sporadic | 0/1 (0) | ||||
| 1 |
2015 May |
−70°C |
Sporadic |
1/1 (100) |
|||||
| GII.4 New Orleans |
GII.P4 New Orleans |
1 |
4.1 × 105 |
0–12 |
1 |
2013 Apr |
−70°C |
Sporadic |
0/1 (0) |
| GII.4 Sydney |
GII.Pe | 22 | 3.5 × 103–2.1 × 107 | 0–12 | 3 | 2012 | −70°C | Sporadic | 1/3 (30) |
| 1 | 2015 Jan | −70°C | Sporadic | 1/1 (100) | |||||
| 7 | 2015 Feb | −70°C | Sporadic | 3/7 (40) | |||||
| 1 | 2015 Mar | −70°C | Sporadic | 1/1 (100) | |||||
| 1 | 2015 Apr | −70°C | Sporadic | 1/1 (100) | |||||
| 1 | 2015 Oct | −70°C | Sporadic | 0/1 (0) | |||||
| 1 | 2016 Apr | −70°C | Sporadic | 0/1 (0) | |||||
| >18 | 1 | 2011 | −70°C | Outbreak | 0/1 (0) | ||||
| 1 | 2013 | −70°C | Outbreak | 0/1 (0) | |||||
| 1 | 2012 May | 4°C | Outbreak | 0/1 (0) | |||||
| 2 | 2016 Apr | 4°C | Outbreak | 1/2 (50) | |||||
| 2 | 2016 May | 4°C | Outbreak | 0/2 (0) | |||||
| GII.P16 | 13 | 0.4 × 103–6.1 × 106 | 0–12 | 2 | 2016 Dec | −70°C | Sporadic | 1/2 (50) | |
| 6 | 2017 Feb | −70°C | Sporadic | 0/6 (0) | |||||
| 5 | 2017 Mar | −70°C | Sporadic | 0/5 (0) | |||||
| GII.P4 New Orleans |
4 |
0.6–14.9 × 104 |
0–12 |
1 | 2015 Jan | −70°C | Sporadic | 0/4 (0) |
|
| 1 | 2017 Jan | −70°C | Sporadic | ||||||
| 1 | 2017 Feb | −70°C | Sporadic | ||||||
| 1 |
2017 Mar |
−70°C |
Sporadic |
||||||
| GII.5 |
GII.P22 |
1 |
1.1 × 104 |
0–12 |
1 |
2010 Nov |
−70°C |
Sporadic |
0/1 (0) |
| GII.6B |
GII.P7 |
1 |
7.6 × 104 |
0–12 |
1 |
2015 Jan |
−70°C |
Sporadic |
0/1 (0) |
| GII.6 |
GII.P7 |
4 |
0.1–8.4 × 106 |
0–12 |
1 | 2012 Dec | −70°C | Sporadic | 0/4 (0) |
| 2 | 2015 Jan | −70°C | Sporadic | ||||||
| 1 |
2017 Jan |
−70°C |
Sporadic |
||||||
| GII.7 |
GII.P7 |
2 |
0.3–9.1 × 106 |
>18 | 1 | 2010 Oct | −70°C | Sporadic | 0/2 (0) |
| 0–12 |
1 |
2012 Aug |
−70°C |
Sporadic |
|||||
| GII.14 |
GII.P7 |
1 |
6.1 × 104 |
0–12 |
1 |
2016 Dec |
−70°C |
Sporadic |
1/1 (100) |
| GII.17 |
GII.Pe |
1 |
3.4 × 105 |
0–12 |
1 |
2010 Oct |
−70°C |
Sporadic |
1/1 (100) |
| GIV |
GIV.P1 |
3 |
0.3–13.6 × 103 |
>18 |
3 |
2016 May |
4°C |
Outbreak |
0/3 (0) |
| Total | 80 | 80 | 16/80 (20) | ||||||