Table 1. Case descriptions of VIM-4–producing Enterobacter cloacae complex nosocomial infections in outbreak involving carbapenemase-producing strains, Lyon, France, January 12, 2014–December 31, 2015*.

Characteristic	Patient no.
	P1	P2	P3	P4	P5	P6	P7
Patient age, y/sex	67/F	72/M	64/F	69/M	87/M	84/F	82/M
Hospitalization duration	10 d	106 d	52 d	26 d	6 d	69 d	36 d
Purpose of hospitalization	Kidney transplant	Peripheral arterial disease	Septic shock	Kidney transplant	Consciousness disorder	Necrotic purpura	Vesical lithotrity
Type of ward	Transplant, medicine	Surgery, medical, ICU	Medical, ICU	Transplant, medical	Medical, ICU	Medical	Surgery, medical, ICU
Antimicrobial therapy before diagnosis†	VAN, OFL, AMX	PTZ, VAN, AMI, MEM,† CTR	CTR, VAN, TZP, MET, AMI, CLI, IMP†	AMX, VAN	AMC	CTR, GEN	CTX, OFL, AMX, PTZ, GEN
Urinary catheter	Yes	Yes	Yes	Yes	Yes	No	Yes
Intubation	No	Yes	Yes	No	No	No	No
Central venous catheter	Yes	Yes	Yes	Yes	No	No	No
In-hospital death: delay from admission, d, and etiology	No	Yes: 106, septic shock from respiratory system	Yes: 52, septic shock, undetermined origin	No	No	No	Yes: 36, septic shock, peritonitis with hemorrhage
Last negative sample;‡ delay from admission, d	Urinary; 7	Urinary; 61	Urinary; 1	Urinary; 20	Rectal swab; 2	Necrotic skin; 39	Urinary; 2
First positive sample	Urinary	Urinary	Urinary	Urinary	Urinary	Necrotic Skin	Peritoneal fluid
Delay from admission, d	32	76	41	29	20	49	28
Delay from last negative sample, d	25	15	40	9	18	10	26
ST	ST873	ST873	ST118	ST873	ST118	ST873	ST110
Isolate identification	C45	C46	C47	C48	C308	C310	C309

*AMI, amikacin; AMX, amoxicillin; AMC, amoxicillin-clavulanate; CLI, clindamycin; CTR, ceftriaxone; CTX, cefotaxime; GEN, gentamicin; ICU, intensive care unit; ICU, intensive care unit; IMP, imipenem; MET, metronidazole; MEM, meropenem; OFL, ofloxacin; PTZ, piperacillin/tazobactam; ST, sequence type; VAN, vancomycin. 
†Carbapenems.
‡For detection of VIM-4–producing Enterobacter cloacae complex.