Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug;24(8):1561–1564. doi: 10.3201/eid2408.180228

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

PMC Copyright notice

Serum IgG reactivity to 3 recombinant antigens in Neisseria meningitidis serogroup B meningococcal vaccine (MenB-4C) (Bexsero; GlaxoSmithKline, Bellaria Rosia, Sovicille, Italy), determined by ELISA. A postmortem serum sample (3) from a 16-year-old girl with paroxysmal nocturnal hemoglobinuria who died of meningococcal disease after treatment with eculizumab. Reactivity was measured in parallel with stored serum from 10 unvaccinated college students (1) and 10 vaccinated college students (2) 7 months after vaccination with MenB-4C (8). For the comparison specimens, each data point represents reactivity of an individual person. A) Factor H binding protein. B) Neisseria heparin binding antigen. C) NadA, MenB-4C antigens absent. OD, optical density. Data points for (3) indicate results of replicate assays. OD, optical density.