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. 2018 Jul 19;11:4159–4166. doi: 10.2147/OTT.S154452

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© 2018 Yang et al. This work is published and licensed by Dove Medical Press Limited

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Effect of protein disulfide isomerase A3 precursor (PDIA3) knockdown on cell growth. Cell death was measured by Cell Counting Kit-8 assay. SW480 (A) and HCT116 (B) cells were incubated with two different small interfering RNA (siRNA)-PDIA3 for 12, 24 and 48 hours, respectively. SW480 cells treated with or without siRNA-PDIA3 were observed under a transmission electron microscope set at 400× magnification (C).

Notes: siRNA-1: 5′-GGACAAGACUGUGGCAUAUTTAUAUGCCACAGUCUUGUCC TT-3′; siRNA-2: 5′-CAGCCAACAAGAAGCUAAATTUUUAGCUUCUUGUUG GCUGTT-3′.