Table 3.II.

Clinical and pathological T for p16 negative oropharyngeal Carcinoma, Eighth Edition TNM (from Amid et al., 2017 ⁴³, mod.).

T category	T criteria
Tx	Primary tumour cannot be assessed
Tis	Carcinoma in situ
T1	Tumour 2 cm or smaller in greatest dimension
T2	Tumour larger than 2 cm but not larger than 4 cm in greatest dimension
T3	Tumour larger than 4 cm in greatest dimension or extension to lingual surface of epiglottis
T4	Moderately advanced or very advanced local disease
T4a	Moderately advanced local disease; tumour invades the larynx, extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible
T4b	Very advanced local disease; tumour invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases carotid artery